You do not need to restart the server for changes to certain configuration files to take effect (for example, obj.conf, mime.types, server.xml, and virtual server-specific ACL files). All you need to do is apply the changes by clicking the Apply link and then clicking the Load Configuration Files button on the Apply Changes screen. If there are errors in installing the new configuration, the previous configuration is restored.
When you edit obj.conf and apply the changes, a new configuration is loaded into memory that contains all of the information from the dynamically configurable files.
Every new connection references the newest configuration. Once the last session referencing a configuration ends, the now unused old configuration is deleted.