By itself, the size of a cluster (number of nodes) does not favor either colocating or not colocating applications and PFS I/O daemons. Larger clusters do, however, attenuate the benefits of colocating. This is because the amount by which colocating reduces network traffic can be expressed as
Tc = Ts - Ts/N
where Tc is the level of network traffic using colocating, Ts is the level of network traffic without colocating, and N is the number of nodes in the cluster. In other words, colocating reduces network traffic by 1/number-of-nodes. The more nodes there are in the cluster, the smaller the effect of colocating.