User Account Control in Windows Server 2008 R2 limits which tasks Standard Users can run.
By default, users are created as Standard Users. Although User Account Control allows Standard Users to temorarily elevate permissions in order to perform administrative tasks, doing so requires administrative credentials.
For more information regarding User Access Control and the permissions granted to each user type, see the Microsoft documentation at http://technet.microsoft.com/en-us/library/cc731416%28WS.10%29.aspx.
The MDEX Engine installation process has changed with the introduction of User Account Control in Windows Server 2008 R2. Because of the resulting security restrictions on tasks that run at elevated privilege, running a per-machine installation of the MDEX Engine now requires administrator permissions. A user may still install a per-user installation without these permissions, but this is not supported in a production environment.