In many applications users can configure their GUI with colors and fonts. In addition, the user profile may have other defaults set as well, such as the date format or the default screen at startup. For the authors creating content, these defaults should all be reset to the defaults in general use at the company. This creates a uniform look and starting place for every topic.
In addition, you should maximize the window for the target application when you are recording content. If the target application's window covers the entire screen, then the Windows desktop icons will not show in the screenshot. If possible, turn off tooltips in the target application as well.