To enable recovery after a failure, you need only back up the database that you use with Oracle Hyperion Calculation Manager, as described in the RDBMS documentation. Additional precautions that you can take:
Back up the product components in EPM_ORACLE_HOME/products/Foundation/CALC.
Perform a weekly full or daily incremental backup of MIDDLEWARE_HOME/user_projects/domains/domain name/servers/managed server name/logs.