Groups of host NICs and Controller ports can be configured into different subnets. Whenever the iSCSI initiator opens a connection to a Controller port, that connection will automatically be routed through the host NIC in the same subnet as the Controller port. For example, if a host has two NIC ports on the iSCSI network, one of the host NIC ports connected to one of the Controller control unit (CU) ports could be placed in one subnet, and another host NIC port connected to the other Controller CU port could be placed in a different subnet.