Inheritance Hierarchy for Blinded and Unblinded Users

This topic describes the inheritance hierarchy for blinded and unblinded users.

Sites, Regions, and Protocols are never blinded or unblinded in Siebel Clinical. It is the users at the different (site, region, or protocol) levels that are either blinded or unblinded. For example, if a user is blinded at site and protocol level but unblinded at the region level, then that user will automatically have blinded access for all site level work like site visits and activities. However, rolling up or down the configuration will change the type of user access accordingly - see the following tables for more information.

Precedence is given to configuration of the Unblinded field for users at site level. If the Unblinded field for a user is updated at site level, then position roll down from protocol and/or region cannot override the Unblinded field definition at site level, since site has more precedence.

Position Rollup

The position roll up hierarchy goes from Site, to Region, and then to Protocol level.

• When you click Position Rollup at site level, all changes (in the Unblinded field for users at site level) will be rolled up to the region and protocol levels.

• When you click Position Rollup at region level, all changes (in the Unblinded field for users at region level) will be rolled up to the protocol level.

The following table shows a user's Unblinded field value after performing a Position Rollup.

Level	User's Unblinded Field Value	Position Rollup?	Unblinded Field Value After Position Rollup
Site	Blinded	Yes, to Region and Protocol levels.	Not Applicable
Region	Unblinded	Yes, to Protocol level.	Blinded
Protocol	Blinded	Not Applicable.	Unblinded if Position Rollup is performed from region level, otherwise Blinded.

Position Rolldown

The position roll down hierarchy goes from Protocol, to Region, and then to Site level.

• When you click Position Rolldown at protocol level, all changes will be rolled down to all the regions and sites for the protocol.

• When you click Position Rolldown at region level, all changes will be rolled down to all the sites for the region.

The following table shows a user's Unblinded field value after performing a Position Rolldown.

Level	User's Unblinded Field Value	Position Rolldown?	Unblinded Field Value After Position Rolldown
Protocol	Blinded	Yes, to Region and Site levels for the selected protocol.	Not Applicable
Region	Unblinded	Yes, to Site level for the selected region.	Blinded
Site	Blinded	Not Applicable.	Blinded Note: If Position Rolldown is performed at Region level, it does not apply since precedence is always given to the value at site level.