Best Practices for Managing the Workflow

In the change type

Use the Assigned to field to set a default assignee. The default assignee receives a notification when the change order is created.
Don't assign the same user as required approver and optional approver.
If you select Allow Updates for interim approval, you can only update header attributes during interim approval.

To detect any errors, use the audit feature during the early stages of the workflow.

Don't enable the root item class for a new item request. Instead, enable it only for that child class which requires the new item request.
Don't assign the same user as required approver and optional approver.

Don’t delete any predefined rule sets available in BPM Worklist.
Create workflow steps that are aligned according to your business processes.
Before you define the entry and exit criteria, review whether a standard workflow already exists.
When you create an approval group, don't include any space in the group name.
Use only the header stage.
Enable notifications based on task status.
In the Assignee tab, don't change any settings.
In the Deadlines tab, don't enable Expiration Settings.
Set vacation rules: You can create a vacation rule so that when you're unavailable, approvals that are assigned to you automatically get reassigned to someone else and the workflow can progress in your absence.

Note:

If you set a vacation rule and if you have multiple approvers, the value of Response Required From must be set to All
Multiple reassignments through vacation rules aren’t supported for the same approval task.