Randomization and kits

The minimization algorithm currently uses the probability factor as the final calculation for a treatment arm to be assigned (former known issue)

Clinical supply managers and statisticians: Previously, the minimization list used the probability factor to determine how subjects are assigned to each treatment arm in a study. Now, the minimization algorithm uses the probability factor to determine the final calculation to balance out the number of subjects on each treatment arm.

Retracted workaround: None. (Issue 33899730)

Open label randomization type available for randomization with cohorts (former known issue)

Study designers: Now, on the Create Randomization dialog, when you select Unblinded for the randomization type, and Adaptive or Demography for the Cohorts field, the None – Open Label option is no longer available for selection, as expected. Previously, on the Randomization drop-down, you could see the None – Open Label available for selection even though, for a randomization with cohorts, this option should not have been available

Retracted workaround: None. (Issue 33082175)

Randomization and kit lists must not contain randomization or kit numbers as decimals (former known issue)

Clinical supply managers and statisticians: Now, when you attempt to upload a kit or randomization list that contains randomization or kit numbers with decimals, the system displays an error message that describes this specific issue. Previously, if you ever uploaded a randomization or kit list with decimal numbers in it, the system did not warn you about the issue.

Retracted workaround: None. (Issue 32565975)