Oracle Clinical One Platform doesn't let the subject titrate

There are multiple situations when a subject might not be allowed to titrate. Depending on the situation, the subject might be able to remain on their current treatment arm, or you might need to reach out to your CRA to learn about other options.

The subject is already on the highest dose or lowest dose

If the subject wants to titrate down but is already on the lowest dose, your options might include maintaining the dose and titrating up, or taking another action specified by the sponsor. Similar rules apply when the subject is already on the highest dose and wants to titrate up. For example, for subjects who have reached their dosing limit, you may receive a message from the sponsor advising you to withdraw the subject from the study.

To learn more about your study settings and what is or isn't allowed, contact your CRA.

Not enough time has passed since the subject last titrated

If not enough time has passed before titration is allowed again, you won't see the options for changing doses. Instead, you go straight through to the Dispense Kits pop-up and see a message letting you know that there's a time limit between titrations. In the meantime, contact your CRA to know more details about the time limit between subject titrations.

The subject has already reached their maximum number of titrations in a study

If this happens, you won't see the options for changing doses. Instead, you go straight through to the Dispense kits pop-up and see a message letting you know that you can't change the subject's dose anymore because they've already changed doses the maximum number of allowed times in the study.

Titration is not available for your study

This means that the study that you're working in doesn't allow titration. In that case, you don't have the ability to change doses for subjects. Instead, you go straight through to the Dispense Kits pop-up like for any other dispensation visit.

If your study allows titration but the titration options don't appear as you expect, contact your CRA.