Can I include Unblinded Pharmacist kits in a kit type titration?
Yes, you can. However, you need to be very careful. Combining regular kit types with kits that can only be dispensed by a pharmacist or unblinded site user, in a kit type titration may, result in the potential unblinding of kits to blinded site users.
When using Unblinded Pharmacist kits in a kit type titration, make sure you also create a treatment arm that contains Unblinded Pharmacist kits with a placebo compound. The Unblinded Pharmacist kits should be defined on both treatment arms of the titration.
If any Unblinded Pharmacist kits are combined with regular kit types in a kit type titration, when performing dose changes, blinded site users will be instructed to contact their unblinded pharmacists for every treatment arm.
Parent topic: Kit and dispensation FAQs (for study designers)