Viewing a sector map (Signals tab)

A sector map for signal management data is a visual presentation of data for a particular drug across all System Organ Classes (SOCs). Each System Organ Class (SOC) is represented by a large tile in the sector map. Smaller tiles within each SOC tile represent Preferred Terms (PTs). The color, size, and ranking of tiles provide a big picture overview of the adverse event profile of a drug. Data represented in the sector map includes all available data up through the current time period and is for a particular signal set.

You view a sector map for a particular drug. PTs are ranked in descending order of values of the statistic (EBGM, EB05, Chi-statistic, or PRR) that you choose. A color key indicates relative ranking. You can also list the ranked PTs below the sector map.

Note: The primary path of a PT is used to determine where it appears in the sector map. If a PT is not in the event hierarchy used for the drug-event combinations, it appears in a SOC tile named Unknown.

The list of ranked PTs below the sector map includes the following information:

1.         Click the Signals tab.

2.         Click Drug Overviews.

3.         Click the row menu () for a drug, and then click View Sector Map for All.

The Sector Map window appears.

4.         If you want to set display options for the sector map, click Options below the sector map.

5.         If you point to a PT tile, the MedDRA PT, HLT, HLGT, and SOC appear. The following information for the combination of the drug and the term that the tile represents also appears:

1. N—Observed number of cases with term.
2. EBGM—Empirical Bayesian Geometric Mean. A more stable estimate than RR; the so-called shrinkage estimate. For more information, see MGPS computations.
3. EB05—A value such that there is approximately a 5% probability that the true Relative Ratio lies below it.
4. PRR—Proportional Reporting Ratio. For more information, see PRR computations.
5. Chi-statistic—Chi-statistic associated with PRR. (If EBGM < 1, the Chi-statistic is expressed as a negative number, indicating that the drug-event combination is more rare than expected). The Chi-statistic is the signed square root of Chi-square.

6.         To zoom in on a particular SOC, click anywhere on the SOC tile and select Zoom from the menu.

7.         If you click a tile for which N is at least 1, a menu appears and you can drill down to cases that include the PT represented by the tile or view statistics for the tile.

8.         To save the graph as an attachment to a topic, click Save to Topic. (This option is available if Links is checked and the Topics feature has been set up.)

9.         To close the Sector Map window, click Cancel.

For information about copying or printing a graph, see Working with results graphs. For best results, print the sector map in landscape mode.