MySQL Shell 8.0
The AdminAPI commands you use to work with an InnoDB Cluster, InnoDB ClusterSet, InnoDB ReplicaSet, and the individual member server instances in these deployments modify the configuration of MySQL Server on the instance. Depending on the way MySQL Shell is connected to an instance and the version of MySQL Server installed on the instance, these configuration changes can be persisted to the instance automatically.
        By making settings to the instance persistent, you ensure that
        after the instance restarts, configuration changes are retained.
        For background information see
        SET
        PERSIST. This persistence is essential for reliable
        usage. For example, if settings are not persistent, an instance
        added to a cluster does not rejoin the cluster after a restart
        because configuration changes are lost.
      
Instances which meet the following requirements support persisting configuration changes automatically:
The instance is running MySQL version 8.0.11 or later.
            persisted_globals_load is
            set to ON.
          
            The instance has not been started with the
            --no-defaults option.
          
Instances which do not meet these requirements do not support persisting configuration changes automatically, and when AdminAPI operations result in changes to the instance's settings to be persisted you receive warnings such as:
WARNING: On instance 'localhost:3320' membership change cannot be persisted since MySQL version 5.7.21 does not support the SET PERSIST command (MySQL version >= 8.0.5 required). Please use the <Dba>.configureLocalInstance command locally to persist the changes.
        When AdminAPI commands are issued against the MySQL instance
        which MySQL Shell is currently running on, in other words, the
        local instance, MySQL Shell persists configuration changes
        directly to the instance. On local instances which support
        persisting configuration changes automatically, configuration
        changes are persisted to the instance's
        mysqld-auto.cnf file, and the configuration
        change does not require any further steps.
      
        You must make the changes locally on local instances that do not
        support persisting configuration changes automatically. For more
        information, see Configuring Instances with
          dba.configureLocalInstance().
      
        When run against a remote instance, in other words, an instance
        other than the one which MySQL Shell is currently running on,
        if the instance supports persisting configuration changes
        automatically, the AdminAPI commands persist configuration
        changes to the instance's mysql-auto.conf
        option file.
      
        If a remote instance does not support persisting configuration
        changes automatically, the AdminAPI commands can not
        automatically configure the instance's option file. So, the
        AdminAPI commands can read information from the instance, for
        example, to display the current configuration. But changes to
        the configuration cannot be persisted to the instance's option
        file. In this case, you need to persist the changes locally. For
        more information, see
        Configuring Instances with
          dba.configureLocalInstance().