Define a Multi-expression Indirect Cost Algorithm

Multiple-expression algorithms can be used to calculate or adjust the value of a cost item. If you have specified the cost as location-scoped, you can define an algorithm for each location.

1. On the Define New Category screen, after providing basic information on the Definition tab and assigning the cost to a service provider on the Assignments tab, select the Algorithm tab.
2. To define an expression, in the Calculate as field, specify the per unit cost value and select the currency for the cost for all locations or each specific location from the currency drop-down list.
   • Editing this field does not convert a previously entered value. ClearTrial assumes that the value you entered is expressed in the chosen currency.
   • When the currency is edited, ClearTrial applies the change to the location-specific costs, unless they have been overridden to vary from the amount and currency entered in this section.
   1. In the per field, specify a percentage value to apply to the selected cost driver for the expression. This percentage will increase or decrease the number derived from the underlying assumption for the driver.
   2. From the of drop-down list, select a unit-based assumption to drive the calculation of this cost.
      • Changes to assumptions that result in an increase or decrease in the number of units for the chosen assumption automatically adjust this cost.
      • User-defined cost drivers appear in the drop-down list in italicized type followed by an asterisk.

      ClearTrial calculates the total value for each location- or study-level expression as the monetary value multiplied by the specified percentage of the number of units expected for the chosen assumption. System-calculated cost values are displayed to the right of the Calculated field and cannot be changed.

   3. You can create algorithms with up to eight individual expressions. To add another expression, click the Add another expression link, then specify the calculation information.
      • Each expression within the algorithm has the ability to use a different cost driver, also known as a Work Unit, a percentage to apply to the cost driver and monetary value.
      • When working with multiple expressions, enter a per cost driver cost, currency, cost driver, and percentage to apply to the cost driver to evaluate to a specific monetary value in a specific currency.
      • If you have specified that the cost varies by location, you can define a specific algorithm for each location.
   4. Click Save, and select the Distribution tab.