What happens when subjects aren't allowed to titrate?
Your next steps depend on the reason the subject wasn't allowed to titrate.
The subject is already on the highest dose or lowest dose
If the subject wants to titrate but is already on the highest dose, then site users can either maintain the same dose, go lower (or higher), or take any other appropriate action according to what the sponsor user or CRO has decided. For example, for subjects who have reached their dosing limit, site users may receive a message from the sponsor advising them to withdraw the subject from the study.
If site users want to learn more about their study settings, they should contact their CRA.
Not enough time has passed since the subject last titrated
Site users shouldn't be able to change doses if not enough time has passed after the last time a subject titrated. Instead, they go straight through to the Dispense Kits pop-up and see a message letting them know that not enough time has passed since the last titration.
If they think they should be able to titrate, but can't, they should contact their CRA to learn more about the study's settings.
To learn more about how to specify when subjects should titrate, see Specify when subjects can titrate
The subject has already reached their maximum number of titrations in a study
If this happens, site users shouldn't see the options for changing doses. Instead, they go straight through to the Dispense kits pop-up and see a message letting them know that they can't change the subject's dose anymore, because they've already changed doses the maximum number of allowed times in the study.
To learn more about how to design a study that allows subjects to titrate, see Define kits for titrations
Titration is not made available for a study
This means that the protocol for the study you are working in doesn't allow titration. In that case, you shouldn't define how subjects titrate, because site users can't change doses for subjects.
Parent topic: Kit and dispensation FAQs (for study designers)