Systems running ESX/ESXi 4.1 support a maximum of 1 TB of memory.
After installing ESX 4.1 on a system with 1 TB of memory, the following message appears:
TSC: 5998092 cpu0:0)Init: 440: 2048 Mb of memory ignored because the system exceeded the supported host physical page number of 268435455...
Workaround
Refer to VMware knowledge base article 1026483 at: