Before creating an Oracle E-Business Suite connection with the Oracle E-Business Suite Adapter, you must perform the setup tasks to ensure it works properly.
If your Oracle E-Business Suite environment is TLS enabled, perform the setup tasks to enable TLS. See: Setup Tasks for a TLS-Enabled Oracle E-Business Suite Environment.
If an XML Gateway message is used as a trigger (source) in an integration, you must perform additional post activation tasks once you activate the integration to ensure the message works properly in Oracle Integration. See: Post Activation Manual Steps for XML Gateway Messages as a Trigger.