Upgrading from Plugin-based DDL Replication to Transaction Log-based DDL Replication
If you are using the plug-in based solution on MySQL 5.7 and plan to upgrade to MySQL 8.0, which uses transaction log based DDL replication, you need to:
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Uninstall the plug-in components as mentioned in Uninstalling Plug-In Based DDL Replication
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Upgrade your database.
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Re-enable DDL replication support based on the steps provided in MySQL: Prerequisites for Transaction Log Based DDL Configuration and check the prerequisites and configuration considerations.